Thursday, March 20, 2025

My Suggestions to Restorin Health and Building Your Energy

 

This  post will complete my series of blogs on toxic chemicals in our environment. After reading all the bad news, if you are still with me you must ask:What to do? Is there a solution? No, there is NO SOLUTION. There are many solutions!                                                                         (It is pretty long and I probably should have put it into several blogs but I am pretty busy and my fingers just kept typing!)

      These are solutions that come to my mind and solutions that our extended family has made over the decades with new “solutions” added as needed. You are welcome to google the net for additional ones  but these are the paths we have chosen in our family and are derived primarily  from our own experience.They are laid down in no particular order and may seem repetitive.

1.     FIRST and FOREMOST. If you fear the health effects of plastic and the associated chemicals. STOP USING PLASTIC. Every suggestion follows from this single golden rule.

2.     . Don’t buy anything in plastic or wrapped in plastic. Ok I get it. In a plastic contaminated world that can seem impossible especially if you are dependent upon an industrial civilization for most of your needs. But start somewhere. Maybe you can reduce it 50% and go from there. Some food items wrapped or shipped in plastic are probably fine from a  toxicity dosage standpoint like frozen meats or vegetables and fruits with a peel or dry goods of all types. Do not buy liquids if possible  because the chemicals from some kinds of plastic can leach out and some are relatively safe. I know which ones based on research I have done . Do your own due diligence. There are types of plastic which don’t shed bisphenols or phthalates or PFAS  for example like PE or HDPE. Most of the toxic chemicals arise from improper disposal such as in landfills which leach the chemicals into the ground water or air.

3.     . Do not heat anything in plastic, EVER. Especially in a microwave. Do not place plastic film over foods in a microwave. Parchment paper or butcher paper works just fine.

4.     Do not buy any food or beverage which has spent significant time in plastic.

5.     Never buy water in plastic bottles. Bring your own tap water with you or buy bottled water in BOTTLES. That is why it was called bottled water!

6.     Grow your own food or get it from someone who does, preferably grown organically. On our little farm we have always had  gardens and pastures and we grow most of our food, make all of our compost, all of our soil. Fruits don’t grow in Wyoming and we don’t consume a lot of fruits because most are heavily dosed with pesticides and herbicides. If you can’t grow your own food or find someone who can for you, maybe you should move.

7.     No Teflon or similar PFAS chemical pots and pans and implements.  Teflon is a PFAS. Teflon is used in things besides pots and pans so educate yourself, in some lids for example. Use CAST iron, SS, ceramic,plain steel or glass or enamel over steel. They have unlimited life and improve over the decades.

8.     Eschew  synthetic fabrics. Wool, Cotton,Flax, linen,silk have worked for 10,000  years.The plastic polymers  like the polyesters and fleece may not transfer anything to your skin directly but  when laundered shed micro plastics into the environment and water supply as micro and nanoplastics. When I got rid of all my polyester clothes I burned them in our wood stove. They should not be recycled to other innocent folks. As an aside I believe the only way to dispose of most all(but not all) plastics is to burn them in a very efficient airtight EPA certified stove without a catalytic converter. VERY high heat is the sine qua non. Never use a burn barrel.

9.     Never use disposable diapers. Always and only cotton diapers. My wife always used a diaper service with our children and ditto my daughter with hers. OK, buy some Pampers if you have to do a trip. Disposable diapers are really hard to remove from the environment. Ask my  Pacific Energy wood stove what she thinks of plastic diapers.

10. Avoid almost all household cleaners and detergents and stain removers. If the label says “miracle” run don’t walk away! PFAS and similar compounds are part and parcel of cleaning agents and detergents whether to clean dishes, clothes, your hands or automobile engines. Good luck with this recommendation. The only true soap I am aware of is Ivory hand soap as well as Dr Bronners liquid. These are the only soaps I will use on my body. The list of ingredients in for example a clothes detergent box takes up most of the box and nowhere does it say there is or was PFAS used in its manufacture but you can be pretty sure it’s there. This goes for most products from our chemical industrial economy.  If you simply cannot avoid their occasional use, reduce the amount radically. IF the Tide box says use ½ cup, try ¼ cup or an 1/8 cup. I assure you it will clean about as well. If you see suds, you used too much. Your washing machine will thank you. These chemicals are hard on the innards of washing machines as my plumber once told me. Research clothes and dish cleaners and there are lots of suggestions including baking soda,vinegar, boarates and others.

11. Avoid most cosmetics or personal care items unless you can verify by an independent assay that it has only benign ingredients. PFAS chemicals abound in cosmetics as well as other toxic chemicals. Most toothpaste has micro plastic granules as polishing and cleaning agents. Read the label. The ingredient will say “toothpaste.”  Informative. MY dad always used Baking soda or tooth powder. I use Baking soda and a water pic and only rarely use floss. FLOSS and PFAS are married to each other. There is a particular PFAS that does wonders for your skin leaving it smooth and soft and glossy. If there is PFAS in a product , rubbing it into your skin will allow rapid absorption into your body. If you are pregnant it will be in your fetus in a New York minute to do damage and bio accumulate. If you are pregnant or trying to be pregnant, be especially mindful because a dose that might pose little risk to you can pose great and prolonged damage to a growing embryo especially in the first 3 or 4 months of gestation. Assume any and all personal and skin care products are harmful and that includes, nail polish mascara, lipstick,rouge, powders, deodorants, conditioners and shampoos, sunscreens and insect repellents and some perfumes. Do your own research. Make your own cosmetics.

12. Hunt or fish for your own meat or if you are out of ammo and worms then raise your own as we do. In our 5  freezers right now we have our Berkshire pigs, Lamb, pork bellies,  and a wide variety of wild game and wild caught fish. Our domestic beef and lamb is 100% grass fed to increase Omega 3’s and decrease Omega 6’s. We have halibut, cod and salmon from a co-op in Alaska. (We formerly fished commercially for salmon and Halibut in the Gulf of Alaska.) We have always had chickens and haven’t bought feedlot eggs in many decades. It is possible to increase beneficial fatty acids like Omega 3’s in your eggs if you really allow them to graze on pasture and also consume insects. We feed them leafy greens like lettuce, spinach and kale in season and all our table scraps. The favorite food of our chickens is turkey and chicken! Buy only raw unpasteurized milk. We no longer milk Daisy, our affectionate Jersey cow but buy from a friend who has a Jersey herd. I make my own butter if we have enough cream and from the butter I make Ghee and clarified butter as well as yoghurt and buttermilk. When we have pigs to raise we feed them a lot of spoiled milk and dairy from a local recycler and it does wonders for the taste of the meat. Danish Hams for example have a diet rich in milk and dairy. I consider commercial milk swill, fit only for pigs.

13. Do not buy any plastic toys and especially old plastic toys. Teething rings are the poster child of pediatric plastic poison  Old plastic toys should be incinerated as they are loaded with Bisphenols and phthalates. Do not send them to the landfill. Avoid letting children play on playgrounds covered with plastic padding or  artificial turf. Phthalates, bisphenols  and micro-nanoplastics are in the dust and can be inhaled. Most especially avoid recycled plastics. Some of the compounds used to recycle them are worse than the parent virgin plastic. Some recycled plastics end up in children’s toys. There should be a special place in hell for the companies that did that.

14.  Avoid plastic school supplies if possible.(I can hear you groaning from here!) Why use a plastic marker if you can use a wooden pencil?

15.  Avoid entirely all use of herbicides, pesticides growth promoters, fungicides, rodenticides. If this isn’t obvious to you by now, you haven’t been paying attention. Roundup for example has a myriad of ingredients besides glyphosate and one scientific article I read said it has 8 of  10  of the characteristics  of a EDC(endocrine disrupting chemical. Have you seen any bees lately, cleaned any insects off your windshield? 70% of insects are gone.  Seen any insect eating birds besides robins?

16. If you live near an airport or military base or old industrial chemical site  and have a well you may have water contaminated with PFAS or other chemicals. Test the water. New tests are available for most chemicals. It is possible to remove many compounds like PFAS with a commercial Reverse Osmosis or ion exchange unit. Many have activated carbon filters attached. Test the water after install and if its still there plan on moving especially if children are present in your household. Good luck selling the house.

17.  Avoid synthetic carpets which have been loaded with PFAS, especially all the old ones. Incinerate them. Newer wall to wall carpets are said to have no or reduced  dirt and water and stain repellent chemicals. They may have something even worse. Expensive wool carpets like Persian carpets with a low weft are a nice expensive substitute. Critters like skin mites and allergenic dusts live in all carpets. Our family has always had throw rugs or braided cotton rugs here and there especially near doors. Wooden floors of course and only wooden floors.  Ok our bathrooms have ceramic tile. We use oil based poly on the floors done every 10 years or more and move out of the house for the week it takes to cure. Varnishes, epoxys and many paints are loaded with PFAS. I know. That is why we go on vacation for a week every 10 years.

18. Avoid buying or driving in new cars.  Buy only used cars. New cars interiors are all plastic which you can smell especially on a hot day. The plastic outgases and condenses on the inside of the windshield and on the inside of your lungs. This diminishes with age and our 25-40 yr old cars and trucks seem to have no odor whatever.  My old Toyotas and Mercedes diesels are mostly leather . Cloth interiors are of course preferable to plastic. If you have to impress the Jones at least drive with your windows open for the first 5 or 10 years! If you use cleaning agents on the inside of your vehicle, the agents may be more toxic than the plastic.

19. Get rid of all plastic food containers. Burn them or send them to the garage to store screws and bolts. Store all food only in Glass, ceramic, steel or aluminum. We use ½ and 1 gallon Ball jars. All cups are ceramic, glass or metal. We have a few Tupperware cups for the grandkids who tend to drop things.

20. Avoid using any disposable anything EVER unless you take it home and incinerate it.

21. Because the route of ingress for many chemicals comes through food it is now time to address that most important of all strategies. My opinions are derived from my own observation and on the work of some amazing researchers like Dr Robert Lustig and his friends and associates. Casey and Calley Means along with RFK  are currently beating the drums about the metabolic syndrome and the obesity epidemic especially in children.  Pay attention to their message even if you don’t favor their politics. Youtube is a good source as well as their excellent books which I have covered previously in this and other blogs I am a retired doctor with an interest in diet and health and I can claim some level of expertise but educate yourself and use your own talents. Starting simple my advice is make and prepare your own foods from fresh ingredients in your own kitchen as often  as you can. Make meals the same as grandma made as Michael  Pollan says. For god’s sake bake your own bread. We make 4 loaves every 2-4 wks and have for 3 decades or more. I avoid takeout and restaurants except on special occasions and never I mean NEVER eat fast food. Never. Did I say Never? There are a few chains which are exceptions and you can figure out which ones. Most serve fast garbage.

22. Avoid Sugar if at all possible with the exception of Dextrose(glucose).  There is no such thing as a healthy artificial sweetener.If you consume sugar in any other form you should limit yourself to 25 gm/day/adult. Less for children  A tbsp is about 12 gm and a tsp about 4. This means honey, maple syrup, molasses as well as others. Table sugar is a synthetic compound of 50%glucose and 50% fructose. The bad guy in this story is the fructose molecule which is toxic in large amounts and ends up just in fat and in your liver. Glucose goes everywhere else .See my older blogs or folks like Bob Lustig for the details. Fructose is one of the root causes of the Metabolic syndrome which encompasses a constellation of diseases like Diabetes, hypertension, Insulin resistance,dyslipidemias, fatty liver disease, dementia and cardiovascular disease among others. The metabolic degradation pathway of fructose is identical to alcohol which should tell you something. To my amazement even the federal government is advising keeping sugar to 25-50 gm a day.

23. Your next problem is avoiding sugar in purchased foods. Some studies have said that it is in 60-70% of processed and grocery store  foods. It is there by design of the Big Food companies and the fast food and sugared beverages industry and  It is there because it is addictive, If it’s addictive, it’s profitable. Throw in some salt and now you are hooked. You should also avoid cakes and cookies and pies except in moderation.  I will give you a little tip. I eat cakes and cookies and pies on occasion but I sweeten with glucose and sometimes some brown sugar or honey. Glucose is not very sweet and sometimes you have to cheat a little.   You will need to purchase it in 50 lb sacks from places like beer supply stores  or Amazon. The small quantities in grocery stores are too expensive. If you want your pancakes to brown you also have to add a little sugar. That is the Maillard reaction. More on that maybe later.

24. Absolutely never EVER buy or consume soft drinks. The amount of fructose in them is huge especially in the worst offenders like Mountain Dew. It will fatten your liver, wreck your waistline and rot your teeth. Look up “Mountain Dew Mouth.”Even big companies like Coca Cola and Monster energy drinks have our chemical friend, Bisphenol, the potent endocrine disruptor in the cans. Use bottles whenever possible. Also drink fruit juices in moderation if at all. Most are loaded with fructose. Eat fruit instead because the fiber in the fruit is the antidote to the fructose. Dried fruits have concentrated fructose especially things like dates and raisins. Never give fruit juice to babies!  I should reinforce a point I have made earlier because this whole obesity epidemic/metabolic syndrome requires a systems analysis. Many of the chemical poisons I have mentioned affect adipocytes and promote increasing size and fat deposition which juxtaposes perfectly with fructose overload. The two are synergistic. Also keep in mind this whole dietary/ chemical disaster is NEW. In the past six or seven decades. Look at movies from the 30’s and 40’s and tell me how many fat people you see. Also how many plastic things do you see?

25. Add fiber to your diet, both the soluble kind and the insoluble kind like in celery. Appropriate amounts of fiber promote gut health.  Fiber is the preferred food for your gut bacteria. If you don’t feed your biome bacteria they may start to feed on you!  On your gut lining. Scanty or absent amounts of fiber cause leaky gut syndrome where the stuff in your gut( essentially, manure!) can leak out through the membrane walls into your blood. Many researchers think that leaky gut is behind the rise in autoimmune diseases because your body’s immune system attacks what’s leaking out and with the right conditions starts attacking the host. That’s you, Bob. A benefit of eating whole fruit and fibrous vegetables  is that it reduces fructose getting into the portal circulation to the liver and sends it down the pipe to the porcelain throne.

26. There are industrial poisons available out there besides in plastics, pesticides pots and pans and cosmetics. No longer are they confined to those industrial sites ringed by railroad tracks along the river. They are right in your neighborhood. Your big box grocery stores. Go in any Krogers or Safeway or Walmart  and you will see whole aisles devoted to sugar saturated breakfast cereals and industrial oils ready for the plucking. Take seed oils for example. There are a host of them. The first oils used in the engine invented by Rudolph Diesel was vegetable oil. Rudolph designed it to use mineral oil which was in short supply but found it ran fine on peanut oil, castor oil, and rapeseed oil. The Japanese battleship Yamamoto was said to be powered with soybean oil. I once ran one of my Mercedes diesels on spoiled olive oil and it ran fine and smelled like a good salad. There are problems  with seed oils. One problem is how they are made. You can get wonderful and healthy oils by pressing them, called expeller pressing, and the oil flows out.  Just filter it. This works fine with products like olives, avocados, coconut and palm oils. Not so fine with soybeans or sunflowers, corn or rapeseed . Ah……Rapeseed…such a horrible name. It had to be renamed to try to sell it and the folks north of the border rebranded it CANOLA (Canada)oil which was initially promoted as a “healthy” oil. Most of the industrial seed oils are anything but. In order to extract them the boys in the lab had to use a lot of heat and chemical solvents, centrifuging them  along with adding other substances to yield a clear liquid which goes into plastic bottles. The lab boys had to use clever marketing to peddle their oils because most of these seed oils are easy to grow in prodigious quantities on the vast croplands of North America and Canada.  They used terms like “polyunsaurated”(=good) instead of saturated(=bad). We know now that was inaccurate. But there was  a kernel of truth in it. Most of these seed oils have a large amount of Linoleic Acid which happens to be one of the “essential” fatty acids which our bodies need for good nutrition. Essential means that our bodies cannot make Linoleic acid, a potent Omega 6 fatty acid. You need Omega 6 FA because it supports inflammation in the body which is needed to do things like attack nasty invaders like viruses and bacteria and promote healing. Your body also needs other fatty acids like the Omega 3’s. Overloading the body with too many Omega 6’s promotes an excess of inflammation. The body needs a balance of Omega 6 to Omega 3. Many authors say a balance of Omega 6 to 3 from 1:1 up to 3:1. But the overuse of these seed oils in frying and processed foods has skewed this ratio to 10 to 20:1 according to some authors. The exact ideal balance is a subject of debate. What is not debatable is that a huge amount of Omega 6 FA promotes too many inflammatory responses in the body. There are other problems beside ultra high heat and yucky stinky solvents to make these oils. Many of these seed oils like from corn and soybeans are grown with huge amounts of herbicides and pesticides unlike other oils like Olives and avocados and coconuts which don’t need these toxic chemicals. The heat and solvents also destroys essential nutrients in the seeds. A big advantage of these industrial oils is their elevated smoke point which is desirable in frying like potato chips. Some of our “good” oils like olive oil has a smoke point of around 300 degrees F which isn’t really high enough for optimal frying. In fact getting olive oil to above its smoke point can convert in from an unsaturated “Cis” fat double bond into a “Trans” double bond and you now have converted a healthy oilive oil fat into a deadly Transfat. That is why you must not fry at high temperatures with olive oil. It is best served cold like on salads and baguettes.  Use other oils like avocado oil or Ghee if you feel you have to fry anything. A huge part of the American diet is fried foods and snacks which have invaded our lives. Presto-Change-o! A population of waddling giant sloths all over the landscape where none existed in the 1940’s when I was born. Have I made this too simplistic? Maybe. Are there

 other factors involved? Of course. Living an urban lifestyle always sitting on your butt in cubicles, cars or a sofa and never getting outside breathing fresh air and exercise is a perfect storm to turn us into a nation of slobs not only here in the good ole US of A but also all over the world. Have you been to Polynesia or England lately? We are not alone. This is a world pandemic.

27. There are other problems in our diet. I personally don’t believe in promoting any particular diet. There are certainly some diets better than others, like a Keto or paleo perhaps but it is not necessary to go to those extremes. Prepare your foods yourself from only fresh safe ingredients and include a lot more fiber and especiialy nuts and seeds. Don’t confine yourself to just peanuts and cashews. Add walnuts and pecans and pumpkin and chia as well as sunflower and hemp seeds for example, especially if they are grown without pesticides or herbicides. Your sperm will love it and really wag their tails!

28. Consider cutting down on “white”  starchy foods like white rice, white flour, white pasta, white sugar and white potatoes. There is a lot of rapidly absorbable glucose in these starches because of their similar molecular branching structure which contributes to their  glycemic index. Their starch is primarily amylopectin. This means they release their glucose rapidly giving you fast high glucose spikes provoking a corresponding insulin spike from your pancreas.  Better to balance the release of glucose from an amylase starch like what you find in beans, legumes and lentils. The glucose in these starches is not laid out in branches like a tree but linearly like in a rope or a chain. So the glucose has to be released or chopped off these chains one by one thus no big insulin and glucose spikes. They have the additional advantage of having a lot of fiber in their coats which makes your gut stand up and cheer.I don’t need to tell you to cut down on white cakes, white bread and donuts which are amylopectin treats saturated with fructose poison.

29. What about meats? I don’t buy the save the planet propaganda by avoiding red meat. However I do avoid buying red or white(!!!) meat grown on feedlots or fish farms with the poor critters stuffed with Omega 6 grains like corn. In our little farm, if we didn’t grow it preferably on grass, we don’t eat it.

     I think I will wrap up this screed by stating a few more obvious ideas which are hardly unique. All of these recommendations come down to adding good foods and behaviors which promote “Good Energy”, the term used by Dr Casy Means in her book of the same name. You get your energy from your mitochondria, the little energy powerhouses inside all your cells. If you feed garbage and chemical poisons to your mitochondria you will have a life marked by fatigue and depression and disease and dementia. What you want are cells loaded with abundant and healthy mitochondria and the way to get to that point you need to get a lot of exercise which allows them to replicate and you need not to poison them with sugar and processed food garbage. See. It’s simple. Not so complicated after all. Good health and good luck.

 


 

 

Saturday, February 22, 2025

The Plastic Problem. Some Culprits:Bisphenols, Phthalates. and PFAS

 In this  and subsequent blogs I  will lay out some of the major classes of chemical compounds in involved in  manufacture and production, distribution, utilization, disposal and recycling of plastics. It is by no means inclusive, just the primary players that we have data points on. More than 350,000 chemical compounds have been made in the past 70 years.  Only about 20% were ever tested in any fashion. There are about 80,000 registered chemicals in the US of whom less than a dozen have been  regulated.(source Linda Birnbaum,podcast with Nate Hagens Jan 21, 2025, The Great simplification.

 Some of these chemicals used in plastics will be familiar to you and others probably not.  The most widely used are bisphenols,  and phthalates and PFAS. . Bisphenols and Phthalates are plasticizers which are added to plastics to increase flexibility, durability, transparency and longevity. They are similar in their effects on biologic systems. They are especially toxic to mollusks, invertebrates. and fish when they show up in bodies of water because they leach out  so readily. They are similar in uses and effects so in a sense talking about them separately can be misleading. Lets start with BPA, Bisphenol A being the poster child.You will likely know it from the baby bottle and sippy cup controversy within the past 15 years. It has long been known as an EDC(endocrine disrupting chemical) and despite hundreds of studies  over decades the FDA responding to the Chemical companies lobbying allowed it to be used in Baby bottles, water bottles and food packaging. But retailers in 2011 and many states did voluntarily remove it from shelves in 2011 responding to consumer pressure and not FDA regulation.. The FDA did nothing for years but finally did ban it from baby food/formula containers in 2013. At this point I feel the need to add a big culprit to my list: The FDA!  It reads: FOOD and DRUGS which is ridiculous on the surface. . It is like having the FAA combined with EPA under one roof. The FDA IMO has failed dismally at regulation of both food and drugs. At the very least it should be broken into two agencies. Another important fact is the the FDA has concerned itself with ACUTE and not chronic toxicity of both food and drugs.  This has been pointed out by many scientists. This applies to both acute and chronic disease and the FDA has ignored chronic disease caused by certain “ foods”. An example is that the FDA has stated there is no risk to high sugar consumption acutely when it has long been known to be  one of the dominant causes of the Metabolic syndrome when consumed  heavily chronically. I have addressed this in a previous blog and will do so in the future. It is also well known that chemicals and additives banned in Europe and Asia are not banned in the US by the FDA. Sorry about that rant. Let us return to our EDC’s………….

      BPA was discovered by Alexandr Dianin in 1891.  An interesting factoid about phthalates  and Bisphenolwas  was their discovery in the 1930’s that they had estrogenic effects  like Bisphenol, when the search was on  worldwide for a synthetic estrogen. We knew 90 years ago  of their potential for endrocrine effects! But these two classes lost out to diethylstilbesterol(DES) being developed about the same time. More on that later. BPA really entered industrial production in the 1950’s with the development of epoxy adhesives and polycarbonate. BPA was mixed with phosgene(YES! one of poison gasses of the first World war!)  and  it made a hard plastic: polycarbonate. Polycarbonate was a durable plastic so hard that it was bulletproof. It was easily formed into cheap food and liquid containers  when it was licensed in 1963 without any published safety information(!). Bisphenol found its way into other plastics such as polyacrylate,polyethylamide,polyester, polyester-styrene, polysulphone.  Also polyethylene(as in water bottles), polyethylene terphthalate(a pthalate) and pvc as a hardening agent, antioxidant and stabilizer. It is still with us and is ubiquitous. It is found in free form on  some thermal printing papers, cosmetics, medical equipment, sports equipment, many toys, clothing, food and drink containers  and other goods.

Bisphenol production(2022) was said to be 10 billion kg/yr. It cannot be usefully and economically recycled (like almost all plastics!!!), and ends up in landfills leaching out into groundwater, dust, dirt and air. The USGS has seen concentrations as high as 6 mg/ltr and Japan has estimated that 84% of all EDC estrogenic activity in their country is due to just to Bisphenol. BPA  can be measured in 93% of all US citizens and it is a cumulative poison. The good news is that its half life is only in days to hours  unlike another class of chemicals we will visit, the “forever chemicals”, PFAS. You would think that Food and drink companies would have removed it decades ago but you would be wrong. Most of the  International soft drink companies like Coca-Cola, Monster energy drinks and General mills still use it because Bisphenol products are part of the business and profit model of  BIG  Processed Food and Big Fast food companies. They continue to use it for food safety considerations and long shelf life which to an extent is true, But it poses other more hidden and delayed food safety risks which they are happy to ignore. These companies and the production companies like Dow, Dupont and their Trade group the American Chemical Council use the well thumbed playbook of the tobacco companies of denial, obfuscation and delay.. I would not accuse them of criminality or evil because it is useful  and fair to look at both sides of an issue. If the FDA says they can use these poisons then they are off the hook when they do. There is a huge database of medical conditions related to just this chemical and its relatives and I will only hit upon some of the more proven established conditions but the potential list is very large. I will also explain the exact biophysiological mechanisms altered and how and why they work to do their nefarious effects.  I realize I may lose a few of you. Sorry!

                                                                                                                                             There has been a steady rise in  population “excess deaths”beginning to rise above baseline in the past several decades and there is no doubt in my mind that this is largely due to  chemical environmental and dietary substances. It is almost guaranteed to be multicausal with a HUGE amount of factors, most of which will be difficult to tease out individually. It will be difficult to remove chemicals like Bisphenol by legislative action but we as individuals can do a lot to reduce their impact on our lives. If we don’t use it, they wont(may not?) make it. I will humbly offer my suggestions  in a future blog.

     Let us look at the mechanism of EDC’s of which BPA  is a big player. BPA looks to the human body like an estrogen or an androgen hormone. It mimics their action on both short and long term metabolism. BY binding to various receptors it can block the action of hormones  even at very low concentrations. For example we know the BPA is an antagonist of the thyroid hormone precursor. It interferes with thyroid synthesis, secretion and signaling.

        We  also hear almost daily about the drop in sperm cell levels and production worldwide, worse in certain regions. BPA  decreases sperm cell motility, and spermatogenesis. That hits both the quantity and quality of sperm. But wait! There’s more. Men exposed to daily elevated levels of BPA show reduced sexual desire and libido, reduced erectile function and orgasms. These effects have been found not only in humans but in mice,cattle, chickens and even fish!!! The signal paper was   a meta study of over 7500 abstracts and papers in 2017 byLevine, Swan, at al., in “Human Reproductive update”.

They said that sperm concentration in the developed world  from 1973 to 2011 had fallen from 99 units to just 47, a compound rate of almost 2%/yr. This has continued since then and even has accelerated in some regions. It is believed that the etiology is chemical toxicity which almost certainly starts early in fetal development and comprises epigenetic factors.(I will address the fascinating  phenomenon of epigenetics in a future blog). This was not good news to the chemical companies and they of course are fighting back. The American Chemical council used the old legal argument:”Correlation is not causation.” This despite a large raft of studies showing exactly that using in vivo and in vitro studies of humans and mammals.       

       As a sidebar I  would like to insert the work of Jeremy Grantham, who authored a paper https://www.gmo.com/americas/research-library/chemical-toxicity-and-the-baby-bust_viewpoints/which created quite a stir about this sperm depletion issue.

                  Jeremy Grantham is a  British investor and philanthropist  who considers this phenomenon of sperm  and  birth decline and deferred childbirth the” greatest threat to the human race”. He focused on this in an excellent paper in 2020 in the publication GMO.com.  entitled “Chemical Toxicity and the Baby Bust.” He posts graphs from the WHO and the US National center for Health Statistics  also showing large jumps in auto immune diseases   such as Type 1 DM, MS, Asthma, Celiac disease and autism. I commend readers to read his excellent paper. Jeremy was influenced by a well known book”Empty Planet: The shock of global Population Decline” published in 2019. I am not persuaded that this is due solely to chemical toxicity . There are other drivers of acute and chronic  disease. The list is not short.

    Let me end this blog. There are more chemical culprits every bit as terrifying as Bisphenol and phthalates. Let us look at the "Forever Chemicals", the PFAS. 

       PFAS stands for per- or polufluoralkyl substances. I should mention that over 350.000 chemicals have been synthesized or released in the last 70 years  and  only a small minority have ever been tested. Among the 80,000 ”regulated “chemicals, only  a small amount have been tested for bio toxicity. There are many many more classes of chemicals which I will not characterize for toxicity. I have chosen just these few classes because they have received a lot of media attention recently. Now to PFAS: PFAS substances are characterized by a Carbon-Fluorine bond of great bond strength. It is its  bond strength which is the chief problem  because strong bonds  mean that is difficult for nature,  the environment or our metabolism to break down the chemical. Fluorine is a member of the halogen Group 17 on the Periodic Table of elements, non metallic elements of great reactivity and unfortunately toxicity.  The main ones are fluorine, chlorine, bromine and iodine and none exist in nature in their free form because they are so reactive. In fact Fluorine is the most reactive element of all. It should be no surprise why it poses potential biotoxicity. Enough chemistry!  As an aside I bring this up to inform the reader to be aware of any chemicals with “fluor” in its name. PFAS chemicals which number 9512(!!!) come in short and long chain variants with the long chain versions thought to pose the greater risk. PFAS are used   in a vast array of products that require dirt, grease and water repellency but also in medical products, cookware, low friction uses(Teflon), fertilizers, pesticides and herbicides, and growth chemicals, cosmetics, building materials, clothing and  most cleaning products. This is just a partial list.
        What are the known and certain health dangers of the PFAS? Let me  paste a summary from a paper from a  National Library  of Medicine paper here:
•    Reproductive and developmental outcomes: PFOS and PFOA exposure leads to a decrease in serum levels of sex hormone-binding globulin (SHBG) in men and follicle-stimulating hormone (FSH) in women. It also negatively affects spermatogenesis and sperm quality, and possibly influences the menstrual cycle. PFAS in the placenta and breast milk may adversely influence fetal or breastfed infants’ development.
•    Immune responses: Exposure to PFAS in infancy and childhood triggers immunosuppression as evidenced by the increased incidence of lower respiratory tract infections and atopic dermatitis. Researchers correlated a modest down-regulation of the C-reactive protein response with PFOA blood levels.
•    Thyroid function: Researchers found a negative correlation between PFAS exposure and serum total thyroxine levels, which indicates PFAS exposure results in thyroid dysfunction and disease. These chemicals can alter human thyroid hormones and potentially contribute to thyroid autoimmunity.
•    Lipid and insulin dysregulation: PFAS exposure leads to an increase in serum cholesterol levels in adults and children. Even a low PFAS dose can increase blood cholesterol levels.
•    Liver disease and cancer: The liver is the primary organ for long-chain PFAS storage, which could subsequently trigger hepatocyte fat infiltration, apoptosis, hepatocellular adenomas, and carcinomas. Scientists observed that PFAS exposure increases alanine aminotransferase levels in the liver which could result in nonalcoholic fatty liver disease (NAFLD).
•            These are just the known health issues that we know today.
•    There almost certainly  will be others to come.
How do these PFAS get into our bodies?  They enter primarily by food and water and contact with our skin or lungs or if you are a fetus through your mother's placenta                                                                     PFAS is in especially high concentration in products like firefighting foams but pose no direct risk  unless you happen to be a fireman or live near an airport or military base where the PFAS/Foam has soaked into the ground and contaminated the aquifer. You get PFAS in food if you eat processed foods, fast foods which come wrapped in pfas coated wraps and containers or things like pizza boxes and microwave popcorn bags. PFAS is in a myriad of cosmetics and skin care products.They make the skin soft and supple and glossy for example.  PFAS is also in shampoos and conditioners, nail polish, toothpaste, sunscreens, dental floss and micropowders. This class of uses may be  especially malignant to people who use a lot of such  items.
       PFAS gets into food in several ways. It can be from runoff into fields and water where crops are grown or animals grazed or from landfills where PFAS has been buried and has leached out. There are 20 million contaminated acres in Michigan and Maine which used  industrial sewage sludge as fertilizer  which was provided “free” by the local municipaliries. The PFAS got into the crops and into the animals bodies and milk and eggs. Non organic foods acquire PFAS from growth regulators and certain fertilizers, pesticides and herbicides. Ultra processed food  and many fast foods are a sure route of ingress coating the wraps and containers of the fast food. What is a person to do? I will address some ideas to mitigate and even eliminate chemical contamination in our lives in a later summary but after reading this it should be obvious that the route to health involves divorcing yourself from our industrial civilization systematically removing known dangerous products and practices and assuming most industrial products are toxic unless proven otherwise . It is a big list but not really that difficult a task. It can be as simple as avoiding miracle fabrics and wear  only cotton,wool or silk clothing. Eliminating virtually all fast food consumption and prepare real food at home.  If food comes with an ingredients list, consider putting it back on the shelf.! Consume Foods that Michael Pollan has said  your grandmother would have brought to the table. Growing your own  organic food  or buying from farm stands and preparing it yourself and limiting “eating out” at restaurants where you have little to no control how food is prepared. These are just a few general ideas of mine which I will address in detail later.
       I need to inform the reader that waiting until research is done elucidating current and future chemical poisons before taking action is a fool’s errand. There is simply no way to know now or ever all the negative sources impacting ourselves and our environment. A large difficulty is simply devising methodologies to do the research. The researcher will be constrained by funding and in the case of evaluating biotoxicity he(she)  will be limited in most cases by use of established cell cultures and cell lines, certain lab animals and timescales, dose/response curves and half lives of chemicals which may or may not translate  over into human physiology. The toxicities will almost certain be different  for different sexes of different ages in different regions with differing individual susceptibilities, coexistent diseases  and metabolism. Good studies may take a long time to perform and in the end not even be conclusive.  The researcher, may not be immune from improper pressures from for example. Big Ag or Big Food or Big Pharma who may be quick to deny, delay or attack conclusions. These giant multinational corporations have owned the turf for many decades and have made a lot of money in the process and will be loath change or stop a lucrative business model. MY advice is YOYO(“You’re on your own”) and Save yourself!

 

 

Saturday, February 15, 2025

The Plastic Problem: overview of the industry

 

       My blogs dealing with the health problems of plastics would be incomplete without looking at the scope of size and importance of the Fossil Fuel and petrochemical industry to the world economy. These are dull but significant statistics but we need to know them to gauge the size of   plastic production now and going forward. You have to include all the  sectors of Oil and gas production. In the US alone Oil and gas employment in the US was 10.3 million people accounting for 8% of US GDP(source:EIA) Worldwide there is said to be more than 65 million people in the energy sector(IEA 2019). Another important factor is that petrochemical feedstock currently accounts for 12% of global oil demand. This slated to increase to 30% by 2030 in only 5 years. As I mentioned in my blog 5 years ago the bulk of petrochemicals is in plastics by weight and volume. 63% of global petrochemicals by weight is plastics.  The remainder excluding fertilizers is non plastic chemicals like paints and adhesives, phrmaceuticals and pesticides,, detergents and cleaners etc ad infinitum.The sectors of plastics are packaging(36%) construction(16%), textiles(15%) vehicles(14%), consumer products(11%) as well as a variety of others in declining parentage  including clothing, electronics etc. A recent paper (Iluminem.com 7/25/2024) said that plastics production will TRIPLE by 2060!!!!  In 2022 it was 400 Million metric tons with an increase to 1231 MILLION metric tons in only 35 years! I give these terrifying numbers as what we are up against if we want to mitigate the disease disaster we will be facing if these increases occur.

       I would invite the reader to look at Google Earth to see the size, impact and location of these companies and I guess I should mention who and where they are just in the US and Europe . Dow Chemical is the gorilla in the room and has plants worldwide with an enormous one at the “Freeport Complex”  south of Houston Texas.  There are many petrochemical plants all along the Gulf Coast as far as Louisiana run by oil companies like Exxon, Occidental, Chevron etc. One of the Europe’s largest is in Ludwigshavn Germany with BASF. The Port Of Antwerp, Belgium has seven of the biggest ten companies on a sprawling site. I am not even including the new plants in the Middle East and China and Asia or South America. But I digress…..

         Returning to the plastic production numbers…... Currently(2022) the world production is 400 MILLION MT. I   have been discussing how serious the plastic problem is now with ONLY 400 million MT. The problem if the world TRIPLES production in the next 3 decades is unimaginable and simply must not happen. To get any faint hope of dealing with this problem we will need to at least flatten the curve and perhaps Cap plastic production. This clearly a global issue requiring global policy initiatives, the most recent being  the  Intergovernmental Negotiating Committee  meeting in Busan South Korea  in late November last year which has been described as a dismal failure to rein in  plastic production. I will try to point out  what leverage we  might have as individual consumers to try to enact policies to limit the health and pollution damage going forward but until we can educate the world population on the extent of the health problem,  the situation is unlikely to change. It is said that when a problem cannot go on it will stop. A nuclear world war or an asteroid impact comparable to the Chicxlub meteor strike 65 million years ago would stop the plastic juggernaut and a worldwide recession might slow it. Ultimately since oil and gas resources are finite,when they terminally deplete plastic production will as well. But humans are also finite and if they deplete, so will the need for plastics. The world will certainly be OK in the long run but the human experiment may not be. We may only have a generation or two left to have even a small hope to arrest this looming crisis. We are of course in the midst of a series of intersecting crises like loss of biodiversity, the climate emergency and pollution. I would include the health disaster of the metabolic syndrome which includes the obesity epidemic, hypertension, diabetes, dementia, cancers and CV disease. I will attempt to show how they are related in a systems analysis. To say this is all very very complex is an understatement. In my next blog I will focus on the types of plastics, their source and probable  toxicity. Down the line I will offer some suggestions on individual strategies to try to save our health and the health of our unborn citizens.